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  • Keptofen

Keptofen

Keptofen

Keptofenkeptofen

Keptofen® 10 %

Ketoprofen

Injectable solution

Pharmaceutical Category:

NSAID

Composition:

Each ml contains 100 mg ketoprofen

Pharmacology:

Ketoprofen exhibits actions similar to that of other NSAIDs in that it possesses antipyretic, analgesic and anti-inflammatory activity. It’s mechanism of action is the inhibition of cyclooxygenase catalysis of arachidonic acid to prostaglandin precursors (endoproxides), thereby inhibiting the synthesis of prostaglandins in tissues. Ketoprofen purportedly has inhibitory activity on lipoxygenase, whereas flunixin reportedly does not at therapeutic doses.

Pharmacokinetics:

Ketoprofen is rapidly absorbed after IM administration. It’s highly distributed throw different body tissues; in horse up to 93% of the drug bound to the plasma albumins (in horses). ketoprofen enter synovial fluid and reach high levels. The onset of activity is within 2 hours and peak effects 12 hours post dose.

Ketoprofen is eliminated via the kidneys as a conjugated metabolite (glocogenic Ester) and unchanged drug. The elimination half life in horses is approximately 1.5 hours.

Target animals:

Cattle, Horses, Dogs and Cats

Administration of ketoprofen up to 5x over labeled dosage in horse dose not exhibit any sign of toxicity.

Indications:

Ketoprofen used as an antipyretic, anti inflammatory and analgesic especially in musculoskeletal disorders.

Horses: Treatment of Synovitis , Artiritis, Tenosynovitis, Osteocondrytis, Laminitis, Colic and soft tissue inflammation after surgery.

Cattle: treatment of mastitis and pneumonia in addition with antibiotic therapy.

Dosage:

Horse: 2.2 mg/kg   BW,   IM or IV injection, once daily, up to 5 days.

Cattle: 3 mg/kg BW, IM or IV injection, once daily, up to 3 days.

The following doses are mentioned in Veterinary drug handbook 4th edition 2002 for these animals:

Dogs: 1 – 2 mg/kg BW, IM, IV or SC injection

Cats: 1 – 2 mg/kg BW, SC injection

Rabbits: 1 mg/kg BW, IM injection q12-24h

Birds: 2 mg/kg BW, IM injection q8-24 hours

Withdrawal time:

Meat: 28 days

Milk: 7 days

Contraindications and Warning:

Do not use in horse during race.

Do not inject in joint.

Do not use if sedimentation occurs.

In cases of GI ulceration, renal or hepatic impairment and late pregnancy using this drug is not recommended.

Storage:

Store at room temperature (below 30°C).

Protect from freezing and direct sunlight.

Keep out of reach and sight of children

Presentation:

50 and 100 ml amber glass vials

 

 

Product License Number from IVO: 88-127-S

For Veterinary Use Only


All rights reserved by Razak Laboratory Co.
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    • Home
    • About us
    • Gallery
      • Labratories
        • Analysis
        • Laboratory
        • Microbiology
        • Production Control
      • Production
      • Research
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    • Organizational Units
      • Laboratory
      • commercial
      • R&D
      • Product Development
      • Production
      • Human Products Sales
      • Vet. Products Sales
    • Product
      • Human Product
        • Antibiotics
          • Tetracycline
          • Tetracycline3%
          • Gemifloxacin Tablet
          • Doxycycline
          • Ciprofloxacin
        • Antihistamines
          • Decongestant
          • Cetirizine
          • Levocetrizine
        • Antipyretic&Analgesic
          • Meloxicam
          • Razofenac 100
          • Reliefen
          • Acetaminophen
          • Cutpain
          • Piroxicam
          • PiroxicamGel
          • Tramadol
          • Celecoxib
          • Diclofenac
          • MefenamicAcid
          • Naproxen
          • coldifen
          • coldstop
        • Cardiovascular
          • tamusin
          • terazosin
          • Amlodipine
          • Amostatine
          • Atorvatatin
          • Enalapril
          • Prazosin
          • Clopidogrel
          • Lisinopril
          • Lozar
          • Carvedilol
        • Herbals
          • Algorella
          • Policosanol
          • pruspitan
          • Talental
          • Thymorant
          • Zoufa
          • Zoufa Asali
          • Fijan
          • Kamoderma
          • Marynthol
        • CNS drugs
          • Alprazolam
          • Thiothixene
          • Trazodone
          • Doxepine
          • Rivastigmine
          • Sertraline
          • Sumatriptan
          • Gabapentin
          • Maprotiline
          • ValproateSodium
        • Supplements
          • Vitamax
          • Zinc-sulphate
          • Foliron
          • Foliron-Zinc
          • Glucosamine
          • Hematinic
        • Dermatologicals
          • herbal burn
          • Adapalen
          • Clinda Plus
          • clindaplus
        • Other
          • AluminiumHydroxide
          • Aluminum gel
          • Expectorant
          • Pioglitazone
          • Tadalafil
          • Tamsolusin
          • Theophyline-G
          • Domperidone
          • Xeniko
          • Metformin
          • Sildenafil&Vigraz
      • Veterinary Products
        • Supplements
          • Ascorvite
          • Oxyvet
          • Aviax
          • Phoscalvit
          • Retivit
          • Tochovit
          • Cholevit
          • Menavit
          • Monensin
          • Nicrab
          • Vitafort
          • Coxistac
        • Vial
          • Adevit
          • Buparvex
          • Dexaphenil
          • Logexin
          • meloxicam
          • Cobaphos
          • Enrocin
          • F-nex
          • Folenx
          • Ivectin
          • Keptofen
          • Lincopec
          • Micosin
          • Oxyflunex
          • Oxyvet
          • Oxyvet-20
          • Theranekron
          • Tyloject
          • Vitafort-B
          • Triprim
      • Download product list
        • Human list
        • Veterinary list
      • RAZAK vet Vademecum
    • Chart
    • Contact Us
    • Home
    • About us
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    • Product
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      • Download product list
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